Norfluoxetine-d5 (propyl-1,1,2,2,3-d5)

Norfluoxetine-d5 (propyl-1,1,2,2,3-d5) - Names and Identifiers

Name	Norfluoxetine-d5 Hydrochloride
Synonyms	Norfluoxetine-d5 Hydrochloride NORFLUOXETINE-D5 HYDROCHLORIDE [2H5]-Norfluoxetine Hydrochloride NORFLUOXETINE-D5 (PROPYL-1,1,2,2,3-D5) Norfluoxetine-d5 (propyl-1,1,2,2,3-d5) γ-[4-(TrifluoroMethyl)phenoxy]benzenepropanaMine 1,1,2,2,3-Pentadeuterio-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
CAS	1185132-92-6

Norfluoxetine-d5 (propyl-1,1,2,2,3-d5) - Physico-chemical Properties

Molecular Formula	C16H17ClF3NO
Molar Mass	331.7604896
Melting Point	145-147°C
Solubility	Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (
Appearance	Solid
Color	White to Off-White
Storage Condition	-20°C Freezer, Under Inert Atmosphere

Norfluoxetine-d5 (propyl-1,1,2,2,3-d5) - Introduction

Norfluoxetine-d5 (Norfluoxetine-d5) is a compound with pharmaceutical properties. It is a metabolite of fluoxetine, a commonly used antidepressant.

The chemical nature of Norfluoxetine-d5 Hydrochloride is a white or off-white powder with the property of being soluble in water. It is a labeled compound in which d5 indicates that the substance is isotopically labeled. This marker is used in research to track and explore the metabolic pathway and efficacy of fluoxetine in vivo.

The primary use of Norfluoxetine-d5 Hydrochloride is as an internal standard for pharmacokinetic and bioequivalence studies. It can evaluate the pharmacokinetic properties of fluoxetine in humans by measuring its metabolism and clearance in vivo. At the same time, this marker can also be used to develop new fluoxetine-related drug metabolic pathways and metabolites.

The preparation method of Norfluoxetine-d5 Hydrochloride is generally to label ordinary Norfluoxetine Hydrochloride by using a deuterated reaction reagent. The specific preparation method requires certain experimental conditions and techniques.

Regarding safety information, Norfluoxetine-d5 Hydrochloride is generally safe under correct use and handling. However, any chemical can be a potential risk. When used, follow appropriate laboratory practices and refer to the relevant safety data sheets and instructions for use.

Last Update：2024-04-09 20:13:35